Fig. 2.

Schematic overview of all experimental groups: Full thickness and chondral defects of osteochondral explants were treated with collagen type I hydrogel (grey) either containing chondrocytes (CHON, blue) or MIX (co-culture of 80% MSCs [orange] and 20% chondrocytes), implanted in chondral or full thickness defects and cultured ex vivo under normoxic (20% O₂, blue frame) or physiological hypoxic conditions (2% O₂, red frame).