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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Comput Methods Biomech Biomed Eng Imaging Vis. 2021 Nov 8;10(5):521–539. doi: 10.1080/21681163.2021.1994471

Figure 3.

Figure 3.

Illustration of the deformable registration workflow applied to Case 9, the most challenging nodule in the dataset: a) mid-slice from the initial lung-centered-RoI image with overlaid non-deformed grid; b) mid-slice from the follow-up lung-centered-RoI (i.e., moving) image with overlaid non-deformed grid; c) scaled moving image with overlaid deformed grid showing the deformation field; d) moving lesion-centered RoI image and corresponding deformed field; e) scaled deformed moving image; subtraction image between the initial and follow-up images before (f) and after (g) registration.