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. 2022 Dec 2;11:e81721. doi: 10.7554/eLife.81721

Table 1. Comparison of organelle marker trafficking characteristics in different model systems from literature.

Model Marker Source Speed in µm/s Fraction Rel. flux in Abs. flux in
Antero Retro Pausing Antero dir. Org./µm/min
Mouse thalamocortical neurons Neuropeptide Y (NPY) Nassal et al. 1.518 1.073 0.13/0.22 0.61/0.82 0.052/0.025
Mouse thalamocortical neurons NPY Knabbe et al. 2.14 1.4 0.11
Mouse sciatic nerve motor neurons HcT/Neurotrophin Sleigh et al. 2.5–2.8* 0.01*
Mouse sciatic nerve sensory neurons HcT/Neurotrophin Sleigh et al. 1.8* 0.005*
Mouse thalamocortical neurons LAMP1 Nassal et al. 2.371 1.476 0.1298 0.54 0.035
Mouse thalamocortical neurons RAB7 Nassal et al. 2.344 1.37 0.085 0.51 0.017
Mouse cultured cortical neurons Sema3A de Wit et al. 0.78 0.43 0.22
Mouse cultured hippocampal neurons NPY Bittins et al. 1.14 0.75 0.023*
Rat cultured hippocampal neurons tPA Kwinter et al. 1.23 1.28 0.16
Rat cultured hippocampal neurons BDNF Cavolo et al. 1.37 1.42
Rat cultured hippocampal neurons LAMP1 Boecker et al. 2 1.5* 0.5$§
Human iPSC derived cultured neurons LAMP1 Boecker et al. 1.5 1* 0.5$§
Mouse cultured hippocampal neurons LAMP1 De Pace et al. 1.7
Mouse cultured hippocampal neurons LAMP1 Snouwaert et al. 0.85* 0.75*
Rat cultured hippocampal neurons RAB7 Boecker et al. 1* 1* 0.29$§
Human iPSC (induced pluripotent stem cell) derived cultured neurons RAB7 Boecker et al. 0.7* 0.9* 0.25$§
Rat cultured cortical neurons RAB7 Castle et al. 0.57 0.57 0.73/0.62§
Rat cultured DRG neurons RAB7 Zhang et al. 0.31 0.53 0.33$
Drosophila larval motor neurons Ilp-2 Lund et al. 0.9* 0.75* 0.1* 0.4*
Drosophila larval motor neurons ANF Sung et al. 0.78* 0.78*
Drosophila larval motor neurons RAB7 Lund et al. 0.9* 0.85* 0.15* 0.25*
Drosophila larval motor neurons Spinster Lund et al. 0.95* 0.85* 0.1* 0.4*
C. elegans larval motor neurons ANF Barkus et al. 1.14 0.41 0.13
*

Values have been estimated from graph in figures, §comparability issues, $values were transformed from original for better comparability.