Table 3.
The IC50 (μg/ml) values of α-amylase and α-glucosidase enzymes inhibitory activities of the crude methanol extract of C. racemosa, its fractions (chloroform, hexane, ethyl acetate, and aqueous), and the standard drug.
| Extract/fraction | Alpha-amylase | Alpha-glucosidase | |
|---|---|---|---|
| IC50 (µg/ml) | |||
| Crude polyphenolic extract | 202.53 ± 2.43 | 399.13 ± 0.89 | |
| Hexane | 538.96 ± 3.73 | 484.96 ± 4.23 | |
| Ethyl acetate | 800.63 ± 4.70 | 153.87 ± 2.37 | |
| Aqueous | 464.20 ± 5.62 | 411.39 ± 1.62 | |
| Chloroform | 451.74 ± 2.14 | 362.34 ± 1.87 | |
| Positive control (acarbose) | 190.07 ± 2.42 | 125.00 ± 1.06 | |