Table 1.
Baseline characteristics of the study population.
| Overall cohort (n = 11,156) | UCR ≤ 100 (n = 8,518) | UCR > 100 (n = 2,638) | p value | ||||
|---|---|---|---|---|---|---|---|
| Age (years) | 77.30 | 12.03 | 76.28 | 12.26 | 80.58 | 10.60 | 0.001* |
| 79 | (71–86) | 79 | (70–85) | 83 | (76–88) | ||
| Male | 5482 | (49.15%) | 4553 | (53.45%) | 929 | (35.22%) | < 0.001* |
| ATSI | 36 | (0.32%) | 31 | (0.36%) | 5 | (0.19%) | 0.293 |
| eGFR (mL/min per 1.73m2) | 45.77 | 16.55 | 46.05 | 16.60 | 44.88 | 16.34 | 0.001* |
| GIT Bleeding | 258 | (2.31%) | 133 | (1.56%) | 125 | (4.74%) | < 0.001* |
| Cardiac failure | 1313 | (11.77%) | 895 | (10.51%) | 418 | (15.85%) | < 0.001* |
| Hypovolaemia | 385 | (3.45%) | 267 | (3.13%) | 118 | (4.47%) | 0.001* |
| Coronary artery disease | 313 | (2.81%) | 231 | (2.71%) | 82 | (3.11%) | 0.281 |
| Cerebrovascular disease | 416 | (3.73%) | 352 | (4.13%) | 64 | (2.43%) | < 0.001* |
| Diabetes mellitus | 3566 | (31.96%) | 2666 | (31.30%) | 900 | (34.12%) | 0.007* |
| CCI score excluding age | 1.57 | 1.85 | 1.53 | 1.83 | 1.68 | 1.92 | 0.001* |
| Serum creatinine ( mol/L) | 136.31 | 93.76 | 139.72 | 102.92 | 125.27 | 53.07 | < 0.001* |
| Serum urea (mmol/L) | 11.15 | 6.53 | 9.76 | 5.57 | 15.64 | 7.32 | < 0.001* |
| Haemoglobin (g/L) | 122.97 | 21.38 | 124.41 | 21.29 | 118.34 | 21.02 | < 0.001* |
| Potassium (mmol/L) | 4.53 | 0.63 | 4.49 | 0.61 | 4.64 | 0.68 | < 0.001* |
| Bicarbonate (mmol/L) | 23.68 | 3.71 | 23.71 | 3.60 | 23.59 | 4.03 | 0.030* |
| Sodium (mmol/L) | 138.67 | 4.26 | 138.64 | 4.20 | 138.75 | 4.47 | 0.239 |
| Albumin (g/L) | 33.75 | 5.28 | 33.86 | 5.27 | 33.40 | 5.31 | < 0.001* |
| ACEi/ARB | 3860 | (34.60%) | 2943 | (34.55%) | 917 | (34.76%) | 0.842 |
| Beta blocker | 3709 | (33.25%) | 2762 | (32.43%) | 947 | (35.90%) | 0.001* |
| Calcium channel blocker | 2380 | (21.33%) | 1852 | (21.74%) | 528 | (20.02%) | 0.058* |
| Loop diuretic | 3487 | (31.26%) | 2446 | (28.72%) | 1041 | (39.46%) | < 0.001* |
| Thiazide diuretic | 1135 | (10.17%) | 785 | (9.22%) | 350 | (13.27%) | < 0.001* |
UCR Urea-to-Creatinine Ration; ATSI Aboriginal or Torres Strait Islander; eGFR Estimated Glomerular Filtration Rate; GIT Gastrointestinal Tract; CCI Charlson Comorbidity Index; ACEi Angiotensin-Converting Enzyme Inhibitor; ARB Angiotensin II Receptor Blocker;
* Patient characteristics with a p value < 0.05 are significantly different between patient groups.