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. 2022 Dec 2;12:20827. doi: 10.1038/s41598-022-25254-7

Table 1.

Baseline characteristics of the study population.

Overall cohort (n = 11,156) UCR ≤ 100 (n = 8,518) UCR > 100 (n = 2,638) p value
Age (years) 77.30 ±12.03 76.28 ± 12.26 80.58 ± 10.60 0.001*
79 (71–86) 79 (70–85) 83 (76–88)
Male 5482 (49.15%) 4553 (53.45%) 929 (35.22%)  < 0.001*
ATSI 36 (0.32%) 31 (0.36%) 5 (0.19%) 0.293
eGFR (mL/min per 1.73m2) 45.77 ± 16.55 46.05 ± 16.60 44.88 ± 16.34 0.001*
GIT Bleeding 258 (2.31%) 133 (1.56%) 125 (4.74%)  < 0.001*
Cardiac failure 1313 (11.77%) 895 (10.51%) 418 (15.85%)  < 0.001*
Hypovolaemia 385 (3.45%) 267 (3.13%) 118 (4.47%) 0.001*
Coronary artery disease 313 (2.81%) 231 (2.71%) 82 (3.11%) 0.281
Cerebrovascular disease 416 (3.73%) 352 (4.13%) 64 (2.43%)  < 0.001*
Diabetes mellitus 3566 (31.96%) 2666 (31.30%) 900 (34.12%) 0.007*
CCI score excluding age 1.57 ± 1.85 1.53 ± 1.83 1.68 ± 1.92 0.001*
Serum creatinine (μ mol/L) 136.31 ± 93.76 139.72 ± 102.92 125.27 ± 53.07  < 0.001*
Serum urea (mmol/L) 11.15 ± 6.53 9.76 ± 5.57 15.64 ± 7.32  < 0.001*
Haemoglobin (g/L) 122.97 ± 21.38 124.41 ± 21.29 118.34 ± 21.02  < 0.001*
Potassium (mmol/L) 4.53 ± 0.63 4.49 ± 0.61 4.64 ± 0.68  < 0.001*
Bicarbonate (mmol/L) 23.68 ± 3.71 23.71 ± 3.60 23.59 ± 4.03 0.030*
Sodium (mmol/L) 138.67 ± 4.26 138.64 ± 4.20 138.75 ± 4.47 0.239
Albumin (g/L) 33.75 ± 5.28 33.86 ± 5.27 33.40 ± 5.31  < 0.001*
ACEi/ARB 3860 (34.60%) 2943 (34.55%) 917 (34.76%) 0.842
Beta blocker 3709 (33.25%) 2762 (32.43%) 947 (35.90%) 0.001*
Calcium channel blocker 2380 (21.33%) 1852 (21.74%) 528 (20.02%) 0.058*
Loop diuretic 3487 (31.26%) 2446 (28.72%) 1041 (39.46%)  < 0.001*
Thiazide diuretic 1135 (10.17%) 785 (9.22%) 350 (13.27%)  < 0.001*

UCR Urea-to-Creatinine Ration; ATSI Aboriginal or Torres Strait Islander; eGFR Estimated Glomerular Filtration Rate; GIT Gastrointestinal Tract; CCI Charlson Comorbidity Index; ACEi Angiotensin-Converting Enzyme Inhibitor; ARB Angiotensin II Receptor Blocker;

* Patient characteristics with a p value < 0.05 are significantly different between patient groups.