Fig. 6.

Comparison of CSAlign and CSAlign-Dock results on the N-terminal domain of the 70 kDa subunit of replication protein A (RPA70N). (a) RPA70N in complex with its inhibitor VU0085636 (PDB ID 5e7n, crystal pose colored in black) [40] and (b) potent inhibitor 1XT (PDB ID 4luz, crystal pose colored in gray) [41]. The top1 poses predicted using (c) CSAlign (orange) and (d) CSAlign-Dock (green) are compared. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)