Table 3.
Count of Inappropriate Classification Above or Below 80 mL/min/1.73 m2 for Each Estimation Equation, by Subpopulation
| Total (N = 637) | Asian (n = 86) | Hispanic (n = 186) | Black (n = 37) | White (n = 328) | |
|---|---|---|---|---|---|
| mGFR, n (%) | 46 (7.2%) | 3 (3.5%) | 6 (3.2%) | 3 (8.1%) | 34 (10.4%) |
| CKDEPI21, n (%) | |||||
| misclass. above | 25 (3.9%) | 2 (2.3%) | 6 (3.2%) | 2 (5.4%) | 15 (4.6%) |
| misclass. below | 57 (8.9%) | 2 (2.3%) | 8 (4.3%) | 8 (21.6%) | 39 (11.9%) |
| total misclass | 82 (12.9%) | 4 (4.7%) | 14 (7.5%) | 10 (27.0%) | 54 (16.5%) |
| CKDEPI09, n (%) | |||||
| misclass. above | 20 (3.1%) | 2 (2.3%) | 4 (2.2%) | 3 (8.1%) | 11 (3.4%) |
| misclass. below | 84 (13.2%) | 6 (7.0%) | 10 (5.4%) | 4 (10.8%) | 64 (19.5%) |
| total misclass | 104 (16.3%) | 8 (9.3%) | 14 (7.5%) | 7 (18.9%) | 75 (22.9%) |
| CKDEPI09-NB, n (%) | |||||
| misclass. above | 19 (3.0%) | 2 (2.3%) | 4 (2.2%) | 2 (5.4%) | 11 (3.4%) |
| misclass. below | 90 (14.1%) | 6 (7.0%) | 10 (5.4%) | 10 (27.0%) | 64 (19.5%) |
| total misclass | 109 (17.1%) | 8 (9.3%) | 14 (7.5%) | 12 (32.4%) | 75 (22.9%) |
| MDRD, n (%) | |||||
| misclass. above | 10 (1.6%) | 2 (2.3%) | 3 (1.6%) | 2 (5.4%) | 3 (0.9%) |
| misclass. below | 180 (28.2%) | 14 (16.3%) | 29 (15.6%) | 7 (18.9%) | 130 (39.6%) |
| total misclass | 190 (29.8%) | 16 (18.6%) | 32 (17.2%) | 9 (24.3%) | 133 (40.5%) |
| MDRD-NB, n (%) | |||||
| misclass. above | 10 (1.6%) | 2 (2.3%) | 3 (1.6%) | 2 (5.4%) | 3 (0.9%) |
| misclass. below | 194 (30.5%) | 14 (16.3%) | 29 (15.6%) | 21 (56.8%) | 130 (39.6%) |
| total misclass | 204 (32.0%) | 16 (18.6%) | 32 (17.2%) | 23 (62.2%) | 133 (40.5%) |
Notes: mGFR and eGFR are measured in mL/min/1.73 m2. Iohexol mGFR denotes measured GFR by iohexol. The term eGFR denotes estimated GFR by the creatinine-based equation with which it is referenced. NB (Non-Black) refers to equations in which the Black race coefficient was omitted; thus, this equation is only applicable to Black participants. Race is based on participant reporting.
Abbreviations: CDKEPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; GFR, glomerular filtration rate; MDRD, Modification of Diet in Renal Disease; mGFR, measured glomerular filtration rate; NB, non-Black.