Table 3.
Impact of nutrient components on MAGE, SD and CV
| Parameter | MAGE (mg/dl) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total person times (n = 32) | Pre-mix insulin regimen (n = 16) | GLP-1 RA on basal insulin regimen (n = 16) | |||||||
| Variable | β | 95% CI of β | P | β | 95% CI of β | p | β | 95% CI of β | p |
| CHO (%) | 1.141 | (− 0.481,2.763) | 0.168 | 2.699 | (0.067,5.332) | 0.045a | 0.918 | (− 1.567, 3.404) | 0.441 |
| Pro (%) | − 6.494 | (− 12.124, -0.865) | 0.023a | − 3.462 | (− 14.797,7.873) | 0.523 | − 2.267 | (− 11.893, 7.358) | 0.621 |
| Fat (%) | − 1.092 | (− 3.013, 0.827) | 0.264 | − 3.487 | (− 6.529, -0.446) | 0.028a | − 1.076 | (− 4.028, 1.876) | 0.448 |
| CHO (gram/kg) | 14.80 | (− 11.941,41.546) | 0.278 | 16.77 | (− 28.008,61.556) | 0.435 | 11.49 | (− 30.454,53.428) | 0.566 |
| Pro (gram/kg) | − 51.39 | (− 123.139,20.357) | 0.160 | − 47.77 | (− 159.053,63.518) | 0.373 | − 18.49 | (− 123.15,86.172) | 0.711 |
| Fat (gram/kg) | − 26.80 | (− 82.136,28.523) | 0.342 | − 67.82 | (− 146.583,10.939) | 0.086 | − 23.13 | (− 107.945, 61.689) | 0.568 |
| Parameter | SD (mg/dl) | ||||||||
| CHO (%) | 0.440 | (− 0.165,1.045) | 0.154 | 1.324 | (0.409,2.239) | 0.008a | 0.266 | (− 0.704,1.235) | 0.566 |
| PRO (%) | − 2.768 | (− 4.786,-0.750) | 0.007v | − 2.854 | (− 7.023,1.315) | 0.164 | − 1.155 | (− 4.849,2.539) | 0.513 |
| Fat (%) | − 0.369 | (− 1.085,0.347) | 0.312 | − 1.595 | (− 2.677–0.513) | 0.007a | − 0.263 | (− 1.419,0.892) | 0.632 |
| CHO (gram/kg) | 4.874 | (− 5.153,14.901) | 0.340 | 8.475 | (− 8.677,25.627) | 0.307 | 4.403 | (− 11.806,20.612) | 0.570 |
| PRO (gram/kg) | − 17.00 | (− 44.015,10.019) | 0.217 | − 21.63 | (− 64.482,21.213) | 0.297 | − 3.635 | (− 44.228,36.959) | 0.851 |
| Fat (gram/kg) | − 5.428 | (− 26.362,15.469) | 0.610 | − 25.17 | (− 56.163,5.821) | 0.103 | − 4.297 | (− 37.377,28.782) | 0.785 |
| Parameter | CV (%) | ||||||||
| CHO (%) | 0.003 | (0.0007,0.006) | 0.011a | 0.004 | (0,0.009) | 0.061 | 0.003 | (− 0.001,0.006) | 0.120 |
| PRO (%) | − 0.013 | (− 0.023,-0.003) | 0.013a | − 0.021 | (− 0.036,-0.006) | 0.009a | − 0.004 | (− 0.019,0.011) | 0.566 |
| Fat (%) | − 0.004 | (− 0.007,-0.0002) | 0.032a | − 0.004 | (− 0.01,0.002) | 0.158 | − 0.004 | (− 0.008,0.001) | 0.095 |
| CHO (gram/kg) | 0.006 | (− 0.041,0.052) | 0.806 | 0.001 | (− 0.075,0.078) | 0.971 | − 0.002 | (− 0.593,0.553) | 0.941 |
| PRO (gram/kg) | − 0.134 | (− 0.243,-0.025) | 0.016a | − 0.187 | (− 0.346,-0.029) | 0.023a | − 0.1 | (− 0.254,0.054) | 0.186 |
| Fat (gram/kg) | − 0.097 | (− 0.182,-0.012) | 0.025a | − 0.113 | (− 0.245,0.018) | 0.085 | − 0.105 | (− 0.225,0.014) | 0.080 |
Linear mixed model analysis with β as standardized coefficient
MAGE mean amplitude of glycemic excursions; SD standard deviation; CV coefficient of variation; CHO carbohydrate; PRO protein
adenotes p value < 0.05