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. 2022 Dec 3;23:311. doi: 10.1186/s12875-022-01898-2

Table 2.

Descriptive statistics for barriers and facilitators to referring patients to clinical trials

Mean (Standard Deviation)
Likelihood of participating in clinical trial referral activities
Refer patients to participate in trial 3.6 (1.7)
Look for active trials for patient 2.0 (1.3)
Conduct preliminary screening for eligibility 2.4 (1.6)
Educate patients about trial participation 2.9 (1.6)
Participate in in-service training about conducting trials 2.6 (1.6)
Barriers: factors preventing referral of patients to clinical trials
No time to assess protocols 5.7 (1.5)
No time to discuss research with patients 5.5 (1.6)
Do not receive recognition for referring patients 3.5 (2.4)
No financial support for participating in referral 3.4 (2.2)
Not aware of what trial opportunities exist 6.2 (1.1)
No clinic-wide process to identify appropriate trials 6.3 (0.9)
Unsure how to evaluate study protocols 4.5 (1.7)
Not knowledgeable about study topic 4.4 (1.7)
Absence of feedback about trial results 3.7 (2.0)
Barriers: provider concerns about patient health management
Study could negatively affect relationship with patients 2.5 (1.7)
Lose control over managing patient’s care 2.4 (1.6)
Uncertainty about health effects of investigational treatments 3.3 (1.7)
Uncertainty about trustworthiness of study sponsor or investigator 2.5 (1.4)
Barriers: patient-related barriers to referral to clinical trials
Patients live too far away from research site 4.1 (1.9)
Study participation is too burdensome for patients 3.9 (1.7)
Patients wary of loss of privacy/confidentiality 3.4 (1.8)
Patients aren’t interested in participating in trials 3.8 (1.5)
Facilitators: factors that would make clinician more likely to refer patients to clinical trials
Introduction to study presented in clinic 4.7 (1.8)
Consistent clinic-level workflow for referring patients 5.2 (1.8)
Electronic health record recruitment alerts 4.3 (2.2)
Documentation of patient enrollment and study outcomes in electronic health record 4.5 (1.8)
Full-time, onsite study coordinator to enroll patients 5.6 (1.7)
Bilingual coordinator to help refer non-English speaking patients 5.0 (1.7)
Dedicated time to participate in research 5.0 (2.0)
Facilitators: importance of trial referral in professional identity
Facilitating clinical trial recruitment is a valuable part of my job 2.4 (1.6)
Referring patients to clinical trials is personally rewarding 2.9 (1.5)
Recommending studies to patients is important to me 3.1 (1.6)