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Topological characteristics of 1D and 2D PPI network models.
| Topological Measure | 1D PPI | 2D PPI | 1D ER | 2D ER |
|---|---|---|---|---|
| Vertices (proteins) | 11,888 | 11,888 | 11,888 | 11,888 |
| Edges (interactions) | 315,130 | 315,130 | 315,130 | 315,130 |
| Faces (triplets) | 0 | 10,451,604 | 0 | 24,948 |
| Euler Characteristic () | − 303,242 | 10,148,362 | − 393,242 | − 278,294 |
1D and 2D network models were compared in the STRINGdb PPI network (PPI) and a random Erdős-Rényi (ER) network with the same number of vertices and edges.
