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. Author manuscript; available in PMC: 2022 Dec 4.
Published in final edited form as: Nat Chem. 2017 Jun 26;9(11):1118–1125. doi: 10.1038/nchem.2803

Figure 1: Measured binodals for the RGG domain and LAF-1.

Figure 1:

The latter is measured in the absence or presence of RNA using ultrafast-scanning FCS approach. a, A schematic illustration of the microscope with an acoustically modulated beam that is controlled by a tunable acoustic gradient index of refraction (TAG) lens. The system focus can be axially scanned along the optical-axis at a frequency of 70 kHz. b, Schematic showing a typical binodal with increasing protein concentration along the abscissa and increasing salt concentration along the ordinate. Our measurements show that the salt concentration decreases the strengths of two-body interactions for RGG domain/LAF-1 systems. c, The measured binodals of the RGG domain as well as LAF-1 in the presence and absence of RNA. Error bars represent the standard deviation (N=10).