Table 2.

Top 2 attitudinal and informational barriers identified from 15 interviews

	COVID-19 vaccine safety concerns	Primary news consumption via social media and politically motivated skepticism
Subpopulation(s) most affected	▪ Hispanic and African American communities ▪ Elderly patients ▪ Immigrant/refugee communities ▪ People with low education ▪ Political conservatives ▪ Religious communities	▪ Anti-vaccination population ▪ Political conservatives ▪ Hispanic and African American communities ▪ Indigenous communities
Related or overlapping barriers	▪ Primary news consumption via social media and politically motivated skepticism ▪ Vaccine hesitancy ▪ Perceived underrepresentation of minorities in clinical trials	▪ Vaccine hesitancy ▪ COVID-19 vaccine safety concerns
Potential solutions	▪ Endorsement/promotion of COVID-19 vaccines by local healthcare professionals, including PCPs ▪ Partner with local leaders and community-based organizations	▪ Endorsement/promotion of COVID-19 vaccines by faith-based organizations ▪ Endorsement/promotion of COVID-19 vaccines by friends and family