Table 1.
Baseline information of subjects categorized by HGI quartiles
| Variables | Q1 (N = 7697) | Q2 (N = 7695) | Q3 (N = 7694) | Q4 (N = 7686) | Overall (N = 30772) |
|---|---|---|---|---|---|
| Clinical data | |||||
| Sex | |||||
| Male | 4260 (55.3%) | 3870 (50.3%) | 3747 (48.7%) | 3951 (51.4%) | 15828 (51.4%) |
| Female | 3437 (44.7%) | 3825 (49.7%) | 3947 (51.3%) | 3735 (48.6%) | 14944 (48.6%) |
| Age(years) | |||||
| Mean (SD) | 42.1 (12.8) | 42.1 (13.0) | 43.8 (13.8) | 49.6 (15.1) | 44.4 (14.1) |
| Median [Min, Max] | 41.0 [19.0, 94.0] | 40.0 [18.0, 94.0] | 42.0 [18.0, 94.0] | 49.0 [18.0, 98.0] | 43.0 [18.0, 98.0] |
| BMI Categories | |||||
| Underweight | 209 (2.7%) | 226 (2.9%) | 199 (2.6%) | 146 (1.9%) | 780 (2.5%) |
| Normal weight | 4480 (58.2%) | 4532 (58.9%) | 4495 (58.4%) | 3860 (50.2%) | 17367 (56.4%) |
| Overweight | 2566 (33.3%) | 2494 (32.4%) | 2503 (32.5%) | 2925 (38.1%) | 10488 (34.1%) |
| Obese | 442 (5.7%) | 443 (5.8%) | 497 (6.5%) | 755 (9.8%) | 2137 (6.9%) |
| Diabetes | |||||
| No | 7208 (93.6%) | 7502 (97.5%) | 7426 (96.5%) | 6273 (81.6%) | 28409 (92.3%) |
| Yes | 489 (6.4%) | 193 (2.5%) | 268 (3.5%) | 1413 (18.4%) | 2363 (7.7%) |
| Hypertension | |||||
| No | 6361 (82.6%) | 6518 (84.7%) | 6548 (85.1%) | 5967 (77.6%) | 25,394 (82.5%) |
| Yes | 1336 (17.4%) | 1177 (15.3%) | 1146 (14.9%) | 1719 (22.4%) | 5378 (17.5%) |
| Hyperuricemia | |||||
| No | 6111 (79.4%) | 6222 (80.9%) | 6263 (81.4%) | 6156 (80.1%) | 24752 (80.4%) |
| Yes | 1586 (20.6%) | 1473 (19.1%) | 1431 (18.6%) | 1530 (19.9%) | 6020 (19.6%) |
| Dyslipidemia | |||||
| No | 4115 (53.5%) | 3950 (51.3%) | 3839 (49.9%) | 3180 (41.4%) | 15084 (49.0%) |
| Yes | 3582 (46.5%) | 3745 (48.7%) | 3855 (50.1%) | 4506 (58.6%) | 15688 (51.0%) |
| Laboratory Results | |||||
| HGB(g/L) | |||||
| Mean (SD) | 148 (15.2) | 145 (15.2) | 144 (15.7) | 144 (16.0) | 145 (15.6) |
| Median [Min, Max] | 148 [73.0, 200] | 145 [70.0, 191] | 144 [70.0, 193] | 144 [66.0, 219] | 145 [66.0, 219] |
| TC(mmol/L) | |||||
| Mean (SD) | 4.79 (0.888) | 4.86 (0.877) | 4.90 (0.906) | 4.99 (0.989) | 4.88 (0.919) |
| Median [Min, Max] | 4.71 [1.97, 11.6] | 4.78 [2.24, 11.7] | 4.83 [2.05, 13.9] | 4.92 [2.10, 12.3] | 4.81 [1.97, 13.9] |
| HDL-C(mmol/L) | |||||
| Mean (SD) | 1.35 (0.353) | 1.37 (0.360) | 1.36 (0.354) | 1.30 (0.347) | 1.35 (0.354) |
| Median [Min, Max] | 1.30 [0, 3.20] | 1.30 [0, 3.00] | 1.30 [0, 3.00] | 1.22 [0.500, 3.38] | 1.30 [0, 3.38] |
| LDL-C(mmol/L) | |||||
| Mean (SD) | 2.84 (0.797) | 2.91 (0.806) | 2.97 (0.838) | 3.08 (0.898) | 2.95 (0.840) |
| Median [Min, Max] | 2.80 [0.500, 8.50] | 2.88 [0.300, 7.55] | 2.90 [0.400, 9.40] | 3.00 [0.500, 10.2] | 2.90 [0.300, 10.2] |
| TG(mmol/L) | |||||
| Mean (SD) | 1.52 (1.39) | 1.42 (1.15) | 1.44 (1.13) | 1.65 (1.45) | 1.51 (1.29) |
| Median [Min, Max] | 1.15 [0.230, 33.2] | 1.12 [0.170, 27.0] | 1.16 [0.210, 23.2] | 1.34 [0.200, 39.6] | 1.19 [0.170, 39.6] |
| BUN(mmol/L) | |||||
| Mean (SD) | 5.03 (1.26) | 5.03 (1.24) | 5.08 (1.27) | 5.29 (1.29) | 5.11 (1.27) |
| Median [Min, Max] | 4.91 [1.57, 16.0] | 4.90 [1.92, 12.9] | 4.93 [1.46, 13.0] | 5.15 [0.86, 16.6] | 4.97 [0.86, 16.6] |
| eGFR(mL/min/1.73m2) | |||||
| Mean (SD) | 109 (13.4) | 108 (13.5) | 107 (14.1) | 103 (15.3) | 107 (14.3) |
| Median [Min, Max] | 110 [36.9, 151] | 110 [30.3, 147] | 108 [34.0, 148] | 103 [30.1, 155] | 108 [30.1, 155] |
| Hcy(m/L) | |||||
| Mean (SD) | 14.9 (9.66) | 14.7 (9.38) | 14.5 (8.66) | 14.8 (9.34) | 14.7 (9.27) |
| Median [Min, Max] | 13.0 [5.00, 186] | 12.0 [5.00, 148] | 12.0 [5.00, 179] | 13.0 [5.00, 179] | 13.0 [5.00, 186] |
| SUA(μmol/L) | |||||
| Mean (SD) | 346 (91.9) | 342 (91.9) | 342 (90.3) | 349 (89.6) | 345 (91.0) |
| Median [Min, Max] | 337 [117, 764] | 332 [100, 773] | 332 [118, 786] | 340 [127, 761] | 335 [100, 786] |
| FBG(mmol/L) | |||||
| Mean (SD) | 5.41 (1.53) | 4.99 (0.86) | 4.88 (0.90) | 5.19 (1.73) | 5.12 (1.32) |
| Median [Min, Max] | 5.08 [3.58, 24.8] | 4.84 [3.45, 18.0] | 4.72 [2.92, 17.6] | 4.72 [2.50, 22.1] | 4.85 [2.50, 24.8] |
| HbA1c(%) | |||||
| Mean (SD) | 5.26 (0.68) | 5.42 (0.42) | 5.59 (0.44) | 6.15 (1.05) | 5.61 (0.77) |
| Median [Min, Max] | 5.20 [2.70, 12.2] | 5.40 [4.60, 11.7] | 5.50 [4.60, 11.8] | 5.80 [4.80, 15.1] | 5.50 [2.70, 15.1] |
| Predicted HbA1c(%) | |||||
| Mean (SD) | 5.74 (0.74) | 5.54 (0.42) | 5.48 (0.44) | 5.63 (0.84) | 5.60 (0.64) |
| Median [Min, Max] | 5.58 [4.85, 15.1] | 5.46 [4.79, 11.8] | 5.41 [4.53, 11.6] | 5.41 [4.33, 13.8] | 5.47 [4.33, 15.1] |
HGI hemoglobin glycation index, BMI body mass index, HGB hemoglobin,TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, Hcy homocysteine, SUA serum uric acid, FBG fasting blood glucose, HbA1c hemoglobin A1c