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. 2022 Nov 30;15:6517–6531. doi: 10.2147/JIR.S380785

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© 2022 Li et al.

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Use of multivariate statistical analysis for the evaluation of plasma lipidomics data (in positive ion mode). (A) PCA score plot. R²X=0.48, LPS group (n=5) and LYC group (n=6) samples fell in Ellipse: Hotelling’s T2 (95%), suggesting that there are no aberrant samples and that the difference between the two groups of samples is significant. (B) OPLS-DA score plot. There were no aberrant samples and the two groups of samples were notably distinct, as shown by the R²Y=0.988, Q²=0.79, and the fact that all of the samples were inside the 95% confidence interval (Hotelling’s T-squared Ellipse). (C) Correlation Coefficient, demonstrating the original model’s robustness and ability to explain the variations between the two groups of samples.