Table 4.
Univariate Logistic Regression Analysis of Risk Factors for Patients with OLGA/OLGIM III–IV
| Risk factors | OLGA I–II VS OLGA III–IV | OLGIM I–II VS OLGIM III–IV | ||||||
|---|---|---|---|---|---|---|---|---|
| OLGA I–II (n = 448) | OLGA III–IV (n = 161) | p-value | OR (95% CI) | OLGIM I–II (n = 370) | OLGIM III–IV (n = 157) | p-value | OR (95% CI) | |
| Gender, Male, n (%) | 265 (59.15) | 94 (58.39) | 0.865 | 0.969 (0.672–1.397) | 200 (54.05) | 83 (52.87) | 0.803 | 0.953 (0.658–1.386) |
| Age, years, mean (SD) | 51.33 (9.78) | 51.10 (10.30) | 0.798 | 0.998 (0.980–1.016) | 49.79 (9.58) | 53.29 (10.39) | <0.001 | 1.036 (1.017–1.057) |
| BMI, kg/m², mean (SD) | 24.32 (2.92) | 24.16 (2.90) | 0.545 | 0.981 (0.922–1.044) | 24.09 (3.27) | 23.97 (3.28) | 0.712 | 0.989 (0.934–1.048) |
| Smoking, n (%) | 185 (41.29) | 68 (42.24) | 0.835 | 1.039 (0.722–1.497) | 161 (43.51) | 64 (40.76) | 0.560 | 0.893 (0.612–1.305) |
| Alcohol consumption, n (%) | 191 (42.63) | 71 (44.10) | 0.747 | 1.061 (0.738–1.526) | 170 (45.95) | 69 (43.95) | 0.674 | 0.922 (0.634–1.343) |
| Family history, n (%) | 34 (7.59) | 26 (16.15) | 0.002 | 2.345 (1.358–4.050) | 30 (8.11) | 28 (17.83) | 0.001 | 2.460 (1.414–4.279) |
| H. pylori infection, n (%) | 172 (38.39) | 87 (54.04) | 0.001 | 1.887 (1.311–2.714) | 121 (32.70) | 84 (53.50) | <0.001 | 2.368 (1.617–3.468) |
| PGI, µg/L Median (IQR) | 107.05 (79.49–141.21) | 79.53 (64.36–107.90) | <0.001 | 0.986 (0.981–0.990) | 101.97 (78.42–132.98) | 85.31 (62.33–122.29) | 0.019 | 0.995 (0.992–0.999) |
| PGII, µg/L Median (IQR) | 10.35 (6.57–17.80) | 9.92 (6.45–14.73) | 0.283 | 0.989 (0.970–1.009) | 8.50 (6.01–13.04) | 13.84 (7.68–20.81) | <0.001 | 1.055 (1.034–1.076) |
| PGR, Median (IQR) | 10.58 (7.34–17.02) | 8.01 (5.86–12.64) | <0.001 | 0.925 (0.888–0.964) | 11.89 (8.73–14.87) | 6.67 (4.98–9.13) | <0.001 | 0.739 (0.695–0.787) |
| G-17, pmol/L Median (IQR) | 2.85 (1.33–7.05) | 3.06 (1.54–9.52) | 0.040 | 1.015 (1.001–1.029) | 2.37 (1.28–5.89) | 4.32 (2.06–14.38) | <0.001 | 1.062 (1.040–1.085) |
Abbreviations: PGI, serum pepsinogen I; PGII, serum pepsinogen II; PGR, pepsinogen I and II ratio; G-17, gastrin-17; BMI, body mass index; SD, standard deviation; IQR, interquartile range.