Table 2.
Clinical and Polysomnographic Characteristic of the Study Population
| Variables | Mild OSA (n=141) | Moderate OSA (n=176) | Severe OSA (n=458) | P |
|---|---|---|---|---|
| Age, year | 43.00(34.00,58.00) | 52.00(38.00,61.00)a | 47.00(37.00,57.00)a | 0.003 |
| Sex, men (%) | 102(72.34%) | 130(73.86%)a | 366(79.91%)ab | <0.001 |
| BMI, Kg/m2 | 28.03±4.85 | 27.84±4.33 a | 30.83±5.07 ab | <0.001 |
| Smoking, n(%) | 79(56.03%) | 101(57.39%) | 250(54.59%) | 0.809 |
| Drinking, n(%) | 73(51.77%) | 98(55.68%) | 253(55.24%) | 0.737 |
| Hypertension,n(%) | 60(42.55%) | 85(48.30%) a | 362(79.04%) ab | <0.001 |
| ESS, score | 5.00(2.00,10.00) | 8.00(4.00,13.00) a | 11.00(6.00,17.00) ab | <0.001 |
| AHI, /hr | 10.10(7.75,12.30) | 21.65(17.93,25.98) a | 59.25(45.98,73.53) ab | <0.001 |
| ArI, /hr | 9.00(5.75,15.45) | 14.45(8.55,22.08) a | 29.10(17.88,43.88) ab | <0.001 |
| ODI, /hr | 8.60(6.15,11.75) | 17.35(13.73,22.37) a | 57.25(41.63,73.40) ab | <0.001 |
| AI, /hr | 1.20(0.30,3.40) | 4.20(1.73,7.85) a | 27.80(12.20,50.93) ab | <0.001 |
| LAT, s | 22.00(14.00,32.50) | 32.75(22.50,45.00) a | 54.75(40.50,70.50) ab | <0.001 |
| MAT, s | 15.10(12.10,18.75) | 18.15(15.00,21.48) a | 23.20(19.48,28.30) ab | <0.001 |
| HI, /hr | 7.90(5.55,10.30) | 16.90(13.25,20.48) a | 27.40(13.68,39.05) ab | <0.001 |
| LHT, s | 48.50(36.00,55.50) | 54.00(44.00,65.13) a | 57.50(48.50,65.63) ab | <0.001 |
| MHT, s | 22.10(19.20,26.55) | 23.00(19.03,28.90) | 24.25(20.80,28.83) a | <0.001 |
| MeanSpO2, % | 96.00(95.00,96.00) | 95.00(94.00,96.00) | 93.00(91.00,95.00) ab | <0.001 |
| MinSpO2, % | 87.00(84.00,89.00) | 84.00(79.00,87.00) a | 72.00(61.00,78.00) ab | <0.001 |
| T90,% | 0.10(0.00,0.90) | 0.70(0.13,2.38) a | 11.80(4.18,32.65) ab | <0.001 |
| Light Hypoxia, n(%) | 133(94.33%) | 156(88.64%) | 131(28.60%) | <0.001 |
| Mild Hypoxia, n(%) | 2(1.42%) | 12(6.82%) | 81(17.69) | |
| Moderate Hypoxia, n(%) | 5(3.55%) | 5(2.84%) | 98(21.40%) | |
| Severe Hypoxia, n(%) | 1(0.71%) | 3(1.70%) | 148(32.31%) |
Notes: Light hypoxia was defined as T90≤5%, mild hypoxia was defined as T90 accounting for 5%-10%, moderate hypoxia was defined as T90 accounting for 10%-25%, severe hypoxia was defined as T90>25%. aIndicates P<0.05 compared with mild OSA group; bIndicates P<0.05 compared with moderate OSA group.
Abbreviations: BMI, body mass index; ESS, Epworth Sleepniess Scale; AHI, apnea hypopnea index; ArI, arousal index; ODI, oxygen desaturation index; AI, apnea index; LAT, longest apnea time; MAT, mean apnea time; HI, hypopnea index; LHT, longest hypopnea time; MHT, mean hypopnea time; meanSpO2, mean percutaneous oxygen saturation; minSpO2, minimum percutaneous oxygen saturation;T90, proportion of cumulative sleep time with oxygen saturationbelow 90% in total sleep time.