Table 3.
Clinical Characteristic of Severe OSA Patients with Different T90 Values
| Variables | Light Hypoxia (n=131) | Mild hypoxia (n=81) | Moderate hypoxia (n=98) | Severe hypoxia (n=148) | P |
|---|---|---|---|---|---|
| Age, year | 51.00(40.00,59.00) | 48.00(48.00,58.50) | 47.00(37.00,62.00) | 42.00(35.00,53.00) a | 0.004 |
| Sex, men (%) | 99(75.57%) | 62(76.54%) | 78(79.59%) | 127(85.81%) | 0.150 |
| BMI, Kg/m2 | 29.67±5.02 | 30.21±3.91 | 30.31±5.33 | 32.52±5.10 abc | <0.001 |
| Smoking, n(%) | 70(53.44%) | 42(51.85%) | 51(52.04%) | 87(58.78%) | 0.654 |
| Drinking, n(%) | 66(50.38%) | 40(49.38%) | 56(57.14%) | 91(61.49%) | 0.183 |
| Hypertension,n(%) | 92(70.23%) | 60(74.07%) | 83(84.69%) ab | 127(85.81%)ab | 0.004 |
| ESS, score | 8.00(3.00,15.00) | 11.00(6.00,17.00) | 10.00(5.00,14.00) | 16.00(9.00,19.00)abc | <0.001 |
| AHI, /hr | 42.70(35.30,56.30) | 52.90(45.70,66.95)a | 60.85(50.90,69.70)a | 74.10(63.83,83.63)abc | <0.001 |
| ArI, /hr | 24.20(10.30,33.60) | 27.90(18.25,40.15) | 32.60(19.85,46.63)a | 36.30(23.23,51.20)ab | <0.001 |
| ODI, /hr | 37.50(28.40,49.20) | 50.90(41.35,62.55)a | 59.40(49.65,68.88)ab | 76.65(64.90,87.48)abc | <0.001 |
| AI, /hr | 12.50(4.30,25.40) | 20.50(11.45,35.30) | 30.20(12.28,50.93) a | 50.75(32.85,64.70)abc | <0.001 |
| LAT, s | 42.50(30.00,56.50) | 51.50(42.25,61.50)a | 56.75(41.75,72.25)a | 67.00(54.00,83.25)abc | <0.001 |
| MAT, s | 19.80(16.90,24.60) | 22.30(20.00,26.90)a | 23.30(19.95,28.33) a | 27.15(22.33,31.00)abc | <0.001 |
| HI, /hr | 28.70(20.70,37.70) | 29.40(19.60,40.35) | 25.90(13.75,40.90) | 18.95(8.23,39.13) ab | 0.006 |
| LHT, s | 57.00(49.00,64.00) | 57.50(49.75,65.50) | 57.00(47.00,66.00) | 58.00(48.00,68.38) | 0.909 |
| MHT, s | 23.90(20.40,27.50) | 23.80(20.10,27.80) | 23.50(20.65,28.83) | 25.75(21.93,30.78) | 0.051 |
| MeanSpO2, % | 95.00(95.00,96.00) | 94.00(94.00,95.00)a | 93.00(92.00,94.00) a | 90.00(87.00,91.00)abc | <0.001 |
| MinSpO2, % | 81.00(78.00,85.00) | 74.00(70.00,78.00)a | 70.00(63.00,75.00)ab | 57.00(47.00,64.00)abc | <0.001 |
Notes: Light hypoxia was defined as T90≤5%, mild hypoxia was defined as T90 accounting for 5%-10%, moderate hypoxia was defined as T90 accounting for 10%-25%, severe hypoxia was defined as T90>25%. aIndicates P<0.01 compared with light hypoxia group; bIndicates P<0.01 compared with mild hypoxia group; cIndicates P<0.01 compared with moderate group.
Abbreviations: T90, proportion of cumulative sleep time with oxygen saturation below 90% in total sleep time; BMI, body mass index; ESS, Epworth Sleepiness Scale; AHI, apnea hypopnea index; ArI, arousal index; ODI, oxygen desaturation index; AI, apnea index; LAT, longest apnea time; MAT, mean apnea time; HI, hypopnea index; LHT, longest hypopnea time; MHT, mean hypopnea time; meanSpO2, mean percutaneous oxygen saturation; minSpO2, minimum percutaneous oxygen saturation.