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Schematic diagram of the model. (a) Serial dilution protocol. PB cells are represented in green, while PF cells are represented in gray. We show 3 days of the experiments. An antibiotic pulse is added during day 3. (b) Segregational loss. Upon cell division, plasmids are segregated at random between the two daughter cells. Then, the plasmids are replicated until the PCN is 4. When a cell inherits no plasmid, it becomes plasmid‐free.
