Fig. 5. E(AH) treatment in human dermal fibroblasts (HDF) leads to inhibition of photoaging-induced secretion of MMP-1 and cytokines.

HDF cells were treated with a Ctl, EGCG, or various concentrations of E(AH) before or after irradiation with UVA (3.0 J/cm²). After 48 h, (A) MMP-1, (B) IL-6, and (C) IL-8 secretion levels in the supernatant were measured by ELISA assay. All data were indicated as mean ± SD of at least three independent experiments. Statistical analysis: *p < 0.05, **p < 0.01, ***p < 0.001 vs. Ctl-treated cells.