Table 1.
IGF1R gene expression in human cancers.
Cancer | Reference |
---|---|
Ovary | Bruchim et al. (84) |
Endometrium | Bruchim et al. (85) |
Breast | Yerushalmi et al. (86) |
Thyroid | Wang et al. (87) |
Colon | Codony-Servat et al. (88) |
Lung | Macaulay et al. (89) |
Stomach | Lowe et al. (90) |
Kidney | Chin and Bondy (91) |
Ewing sarcoma | Mancarella and Scotlandi (27) |
Brain | García-Segura et al. (54) |
Enhanced IGF1R gene expression constitutes a common feature of most human cancers. IGF1Rs in tumors have been characterized using competitive binding assays, affinity cross-linking, Northern blots, RNase protection assays, RT-PCR, or a combination of them. The table represents a partial list of tumors in which IGF1R is highly expressed.