Figure 4.
Enrichment analysis. GO (A) and GSEA (B) enrichment analyses of DEGs between PDTC/ATC and PTC samples. (C) Co-expression heatmap of top 10 positively associated genes and top 10 negatively associated genes with MMP1 form TGGA PTC samples. (D) GO and KEGG enrichment analyses of main associated genes of MMP1. GEO, the Gene Expression Omnibus; PDTC, poorly differentiated thyroid cancer; ATC, anaplastic thyroid cancer; PTC, papillary thyroid cancer; TCGA, The Cancer Genome Atlas; GO, Gene Ontology; GSEA, Gene set enrichment analysis; KEGG, Kyoto Encyclopedia of Genes and Genomes; NES, normalized enrichment score; BP, Biological Process; CC, Cellular Component; MF, Molecular Function; ***P <0.001.