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. 2022 Nov 21;13:1022850. doi: 10.3389/fimmu.2022.1022850

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Copyright © 2022 Deng, Zhao, Lv, Ma, Zhang, Xu, Zhou, Chen and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlations between MMP-associated gene levels and the levels of infiltrating immune cells determined by CIBERSORT. Differences in the levels of infiltrating immune cells between the CD and UC groups in the Combined Datasets (A) and the GSE75214 dataset (B). Correlations between the MMP-associated gene levels and immune cell levels were further examined by a Spearman correlation analysis in the Combined Datasets (C) and the GSE75214 dataset (D), and results with significant differences are shown (*p < 0.05, **p < 0.01). The results, including data regarding other MMP-associated genes, including CXCL13, MMP3, MMP1 and CXCL1, are illustrated in Supplementary Figure 2 .