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. 2022 Nov 21;13:1022850. doi: 10.3389/fimmu.2022.1022850

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Copyright © 2022 Deng, Zhao, Lv, Ma, Zhang, Xu, Zhou, Chen and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of DEGs by an RRA analysis and functional enrichment analysis. Volcano plots of the DEG distributions in the GSE75214 (A), GSE10616 (B), GSE36807 (C), and GSE9686 (D) datasets. Upregulated genes are indicated by red points, while downregulated genes are indicated by green points. Genes with no significant differences in levels are indicated by black points. (E) Heatmap of the expression data of the top 10 DEGs identified in the RRA. The genes upregulated in CD are indicated in blue, and those upregulated in UC are indicated in orange. Functional enrichment analysis of DEGs, including (F) a GO-BP analysis and (G) a KEGG pathway analysis.