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. 2022 Nov 21;13:1059771. doi: 10.3389/fimmu.2022.1059771

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Copyright © 2022 Liu, Lin, Cao, Wang and Sui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The stereo view of the binding paratopes of Fab (A) (PDB: 1IGT), VHH (B) (PDB: 1I3V) and VNAR (c) (PDB: 2CDQ) (25), Copyright ^© 2017 Elsevier. (D, E) represent two examples of the geometrical VHH structures in the “best-fit ellipsoidal model”, PDB: 1BZQ for (D) and PDB: 5OVW for (E), while axe a-c represents the depth, width and length, respectively (14), Copyright ^© 2018 Elsevier.