Fig. 5.
(a) MR-FLAIR axial sequence shows a rounded area of hyper-intensity at the splenium of corpus callosum (white arrow). (b) This lesion is hypo-intense on T1-weighted imaging (white arrow) and involves a diffusivity restriction on (c, d) DWI/ADC maps (white arrows). This lesion is reversible and is due to an (ex)citotoxic edema mediated by COVID-19. ADC, apparent diffusion coefficient; DWI, diffusion-weighted imaging; FLAIR, fluid-attenuated inversion recovery; MR, magnetic resonance imaging.