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. 2022 Nov 20;25(11):803–810. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2022.102.47

表 5.

178例免疫治疗NSCLC患者PFS单因素与多因素Cox回归分析

Univariate and multivariate Cox regression analysis of PFS in 178 treated with immunotherapy NSCLC patients

Characteristics Univariate analysis Multivariate analysis
HR (95%CI) P HR (95%CI) P
Age (< 65 yr vs ≥65 yr) 1.017 (0.734-1.410) 0.918
Gender (Female vs Male) 1.310 (0.885-1.940) 0.177
ECOG PS (0-1 vs 2) 1.907 (1.270-2.865) 0.002 1.275 (0.827-1.966) 0.272
Smoking (Yes vs No) 1.103 (0.804-1.514) 0.543
Histology (Squamous vs Non-squamous) 1.030 (0.751-1.411) 0.855
TNM stage (III vs IV) 1.330 (0.962-1.839) 0.085
Lines of treatment (1 vs ≥2) 1.126 (0.803-1.579) 0.493
Option of treatment (Monotherapy vs Combination therapy) 0.762 (0.496-1.170) 0.214
DNLR (< 0 vs ≥0) 1.162 (0.844-1.600) 0.357
NLR (< 5 vs ≥5) 2.318 (1.627-3.303) < 0.001 1.440 (0.943-2.198) 0.091
dNLR (≤3 vs > 3) 1.862 (1.352-2.565) < 0.001 1.546 (1.068-2.238) 0.021
LDH (≤245 IU/L vs > 245 IU/L) 2.399 (1.724-3.339) < 0.001 2.065 (1.444-2.954) < 0.001