表 1.
人肺腺癌细胞株PC9、PC9/BB4、A549细胞株对吉非替尼、STE029的IC50
Comparison of Gefitinib IC50 and STE029 IC50 in PC9, PC9/BB4, A549 cell lines
| Index | IC50 (μmol/L) (Mean, 95%CI) | P | ||
| PC9 | PC9/BB4 | A549 | ||
| a: comparison between PC9 cell lines and PC9/BB4 cell lines; b: comparison between PC9 cell lines and A549 cell lines; c: comparison between PC9/BB4 cell lines and A549 cell lines. IC50: 50% inhibitory concentration. | ||||
| Gefitinib | 0.12 (0.07-0.21) | 11.41 (10.67-12.20) | 14.39 (13.32-15.55) | 0.001a |
| < 0.000,1b | ||||
| 0.054c | ||||
| STE029 | 2.48 (2.17-2.85) | 7.80 (5.92-10.26) | 8.26 (7.64-8.92) | 0.005a |
| 0.007b | ||||
| 0.320c | ||||