TABLE 3.
Effect of immunization with pneumococcal proteins on nasal carriage of E134
| Immunogens | No. of mice | CFU/nasal wash (mean log [standard error]) |
P value of immunogen(s) versus CTB only
|
|
|---|---|---|---|---|
| Student's t test | Wilcoxon test | |||
| CTB only | 11 | 4.94 (0.30) | ||
| PspA | 10 | 4.32 (0.42) | 0.24 | 0.43 |
| PsaA | 10 | 3.51 (0.36) | 0.0061 | 0.0062 |
| PdB | 4 | 4.64 (0.40) | 0.60 | 0.75 |
| PspA + PsaA | 10 | 2.45 (0.31) | <0.0001 | <0.0001 |
| PspA + PdB | 4 | 4.16 (0.37) | 0.18 | 0.23 |