Table 2.
Univariable and multivariable regression analysis of determinants of timing of sICH after endovascular stroke treatment.
| Variables | β (95% CI) | Adjusted β (95% CI) |
|---|---|---|
| Age (per 10 years) | 1.03 (0.80–1.32) | 0.88 (0.65–1.20) |
| Male sex | 1.12 (0.61–2.05) | 0.85 (0.44–1.65) |
| Medical history of stroke | 0.65 (0.28–1.51) | 0.52 (0.19–1.41) |
| Medical history of atrial fibrillation | 1.76 (0.83–3.74) | 1.45 (0.55–3.83) |
| Medical history of vascular disease | 1.16 (0.57–2.37) | 0.98 (0.44–2.20) |
| Prior use of antiplatelets | 0.97 (0.53–1.78) | 1.33 (0.64–2.78) |
| Prior use of anticoagulants | 2.03 (0.80–5.17) | 1.88 (0.55–6.47) |
| Baseline NIHSS (per point increase) | 1.03 (0.98–1.09) | 1.05 (0.99–1.11) |
| Baseline systolic blood pressure (per 10 mmHg) | 1.02 (0.92–1.15) | 1.05 (0.92–1.19) |
| Baseline glucose level (per mmol/L) | 1.00 (0.96–1.04) | 0.97 (0.92–1.01) |
| Baseline platelet count (per 10 ×109/L) | 1.00 (0.96–1.03) | 1.00 (0.96–1.04) |
| Baseline INR (per point increase) | 2.20 (0.86–5.59) | 2.54 (0.73–8.92) |
| Baseline ASPECTS on NCCT (per point increase) | 0.92 (0.79–1.08) | 0.87 (0.73–1.04) |
| Poor collateral score (<50%) | 0.89 (0.49–1.65) | 0.82 (0.42–1.60) |
| Intravenous alteplase treatment | 0.99 (0.46–2.13) | 1.68 (0.66–4.26) |
| Performed procedure (EVT vs DSA or catheterization only) | 0.64 (0.25–1.64) | 0.52 (0.19–1.41) |
| Poor post-EVT mTICI score (<2B) | 0.68 (0.37–1.25) | 0.59 (0.31–1.11) |
| Onset to reperfusion time (per hour) | 1.00 (1.00–1.01) | 1.00 (1.00–1.01) |
Univariable and multivariable regression coefficients are presented as beta (β) coefficients with 95% confidence intervals (CI). sICH: symptomatic intracranial hemorrhage; NIHSS: National Institutes of Health Stroke Scale; INR: International Normalized Ratio; ASPECTS: Alberta Stroke Program Early CT score; NCCT: Non-Contrast CT; EVT: Endovascular Therapy; DSA: Digital Subtraction Angiography; mTICI: modified Thrombolysis in Cerebral Infarction.