Table 1.
Stage | Assessments | |
---|---|---|
Acute kidney injury | Serum Creatinine Concentration | Urine Output |
1 | 1.5–1.9× baseline or ≥0.3 mg/dl above baseline | <0.5 ml/kg/hr for 6–12 hr |
2 | 2.0–2.9× baseline | <0.5 ml/kg/hr for >12 hr |
3 | ≥3.0× baseline, ≥4.0 mg/dl, or initiation of renal-replacement therapy | <0.3 ml/kg/hr for ≥24 hr or anuria for ≥12 hr |
Chronic kidney disease | Definition | GFR |
ml/min/1.73 m 2 | ||
1 | Kidney damage with normal GFR | ≥90 |
2 | Kidney damage with mild decrease in GFR | 60–89 |
3A | Mild-to-moderate decrease in GFR | 45–59 |
3B | Moderate-to-severe decrease in GFR | 30–44 |
4 | Severe decrease in GFR | 15–29 |
5 | End-stage renal disease | <15 |
The stage of acute kidney injury is determined according to the Kidney Disease Improving Global Outcomes Acute Kidney Injury Classification,6 and that of chronic kidney disease according to the glomerular filtration rate (GFR).2 Kidney damage is usually detected by means of an increased urinary albumin-to-creatinine ratio. To convert the values for creatinine to micromoles per liter, multiply by 88.4.