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. 2022 Dec 5;23:72. doi: 10.1186/s12868-022-00750-8

Table 1.

Patient characteristics and genetic types of WHO II-IV gliomas

Characteristics LGGs HGGs Total P value
WHO II
n = 36 (32.43%)
WHO III
n = 32 (28.83%)
WHO IV
n = 43 (38.74%)
WHO II-IV
n = 111 (100.00%)
LGGs vs
HGGs
Age 42.4 ±11.6 46.5 ±12.4 57.8 ±15.0 44.3 ±12.1 P < 0.0001
Sex P = 0.035
 Male 24 (66.67%) 19 (59.38%) 15 (34.88%) 58 (52.25%)
 Female 12 (33.33%) 13 (40.62%) 28 (65.12%) 53 (47.75%)
Genetic type
 IDH P < 0.0001
  Mutation 27 (75.00%) 15 (46.88%) 3 (6.98%) 45 (40.54%)
  Wildtype 9 (25.00%) 17 (53.12%) 39 (90.70%) 65 (58.56%)
  NA 0 (0.00%) 0 (0.00%) 1 (2.32%) 1 (0.90%)
 MGMT P = 0.002
  Methylated 28 (77.78%) 21 (65.63%) 17 (39.53%) 66 (59.46%)
  Unmethylated 6 (16.67%) 10 (31.25%) 26 (60.47%) 42 (37.84%)
  NA 2 (5.55%) 1 (3.12%) 0 (0.00%) 3 (2.70%)
 TERT P = 0.471
  Mutation 17 (47.22%) 13 (40.62%) 25 (58.14%) 55 (49.55%)
  Wildtype 17 (47.22%) 15 (46.88%) 13 (30.23%) 45 (40.54%)
  NA 2 (5.56%) 4 (12.50%) 5 (11.63%) 11 (9.91%)

Unless otherwise noted, data in the table are presented as n (%) or mean ± standard deviation; NA: not available

LGGs low grade gliomas; HGGs high grade gliomas