Table 1.
Characteristics | LGGs | HGGs | Total | P value | |
---|---|---|---|---|---|
WHO II n = 36 (32.43%) |
WHO III n = 32 (28.83%) |
WHO IV n = 43 (38.74%) |
WHO II-IV n = 111 (100.00%) |
LGGs vs HGGs |
|
Age | 42.4 | 46.5 | 57.8 | 44.3 | P < 0.0001 |
Sex | P = 0.035 | ||||
Male | 24 (66.67%) | 19 (59.38%) | 15 (34.88%) | 58 (52.25%) | |
Female | 12 (33.33%) | 13 (40.62%) | 28 (65.12%) | 53 (47.75%) | |
Genetic type | |||||
IDH | P < 0.0001 | ||||
Mutation | 27 (75.00%) | 15 (46.88%) | 3 (6.98%) | 45 (40.54%) | |
Wildtype | 9 (25.00%) | 17 (53.12%) | 39 (90.70%) | 65 (58.56%) | |
NA | 0 (0.00%) | 0 (0.00%) | 1 (2.32%) | 1 (0.90%) | |
MGMT | P = 0.002 | ||||
Methylated | 28 (77.78%) | 21 (65.63%) | 17 (39.53%) | 66 (59.46%) | |
Unmethylated | 6 (16.67%) | 10 (31.25%) | 26 (60.47%) | 42 (37.84%) | |
NA | 2 (5.55%) | 1 (3.12%) | 0 (0.00%) | 3 (2.70%) | |
TERT | P = 0.471 | ||||
Mutation | 17 (47.22%) | 13 (40.62%) | 25 (58.14%) | 55 (49.55%) | |
Wildtype | 17 (47.22%) | 15 (46.88%) | 13 (30.23%) | 45 (40.54%) | |
NA | 2 (5.56%) | 4 (12.50%) | 5 (11.63%) | 11 (9.91%) |
Unless otherwise noted, data in the table are presented as n (%) or mean standard deviation; NA: not available
LGGs low grade gliomas; HGGs high grade gliomas