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. 2022 Dec 5;17:92. doi: 10.1186/s13000-022-01273-w

Table 2.

Immunohistochemical staining patterns and mutational analysis of TP53

Mutation type Immunohistochemical pattern of p53 Total
Overexpression Null type Usual
SNV 65 (75.6) 0 (0) 0 (0) 65
Frameshift indel 0 (0) 7 (25) 0 (0) 7
In-frame indel 4 (4.7) 0 (0) 0 (0) 4
Truncation 1 (1.2) 9 (32.1) 0 (0) 10
Copy-number loss 1 (1.2) 0 (0) 0 (0) 1
Splice 2 (2.3) 7 (25) 0 (0) 9
SNV/Frameshift indel 1 (1.2) 1 (3.6) 0 (0) 2
SNV/SNV 5 (5.8) 0 (0) 0 (0) 5
Splice/Truncation 0 (0) 1 (3.6) 0 (0) 1
Wild type 7 (8.1) 3 (10.7) 21 (100) 31
Total 86 28 21 135

The corresponding percentages are shown in parentheses