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Immunohisochemical staining pattern of p53 according to MDM2 amplification status
| MDM2 amplification status | ||
|---|---|---|
| No amplification | Amplification | |
| Null type | 27 (22.0) | 1 (8.3)a |
| Usual | 13 (10.6) | 8 (66.7) |
| Overexpression | 83 (67.5) | 3 (25.0) |
| Total | 123 | 12 |
The corresponding percentages are shown in parentheses
a This case harbored TP53 compound R337C and E204Gfs*43 mutations and classified as DISRUPTED in main analysis
