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. 2022 Dec 5;17:92. doi: 10.1186/s13000-022-01273-w

Table 6.

Immunohistochemical staining patterns according to the TP53 mutation types in MDM2-amplified cases

TP53 mutation types Immunohistochemical pattern of p53
Overexpression Null type Usual
IF-DBD 2 (66.7) 0 (0) 0 (0)
DISDRUPTED 0 (0) 1 (100) 0 (0)
Wild type 1 (33.3) 0 (0) 8 (100)
Total 3 1 8

The corresponding percentages are shown in parentheses