TABLE 4.
Microscopic findings in germfree piglets inoculated with isogenic E. coli strains expressing or not expressing CNF1 toxin and then euthanized 24 h postinoculation
| Microscopic finding(s) | % Piglets with lesionsa inoculated with:
|
|
|---|---|---|
| M623 (n = 6) | M623ΔCNF1 (n = 7) | |
| Pulmonary interstitial inflammation | 66 | 14 |
| Pulmonary alveolar inflammation | 33 | 14 |
| Bronchio-alveolar necrosis | 17 | 0 |
| Renal congestion and/or hemorrhage | 50 | 57 |
| Intestinal congestion and/or hemorrhage | 50 | 50b |
a
Piglets were inoculated with M623 or M623ΔCNF1 E. coli strains.
b
The analysis of one piglet could not be realized.