Table 2.

Particle size of immune complexes.

	Volume-Particle size
	Peak (d.nm)	Mean (d.nm)
Control IgG alone	8.7	10.2
Control IgG + NGF	8.7	9.5
anti-NGF IgG alone	8.7	10.3
anti-NGF IgG + NGF	37.8	52.9
anti-NGF Fab’-PEG alone	11.7	17.2
anti-NGF Fab’-PEG + NGF	15.7	23.2

DLS analysis was used to detect the particle size of the immune complexes. Peak and mean diameters (nm) based on volume particle size distributions (shown in Figure 4a) were measured using Zetasizer Nano.