Chu 2008.
Methods | RCT | |
Participants | Volunteers aged 18 to 45 recruited via flyers and word of mouth from University and local physician referral. Depression severity mild to moderate, if severe required written permission from physician. Mean age 26.4 (18 to 43). 100% women. |
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Interventions | For 10 weeks: 1. Up to 5 high‐intensity aerobic exercise sessions per week (1 supervised) to expend 1000 Kcal per week (n = 15) 2. Up to 5 low‐intensity aerobic exercise sessions per week (1 supervised) to expend 1000 Kcal per week (n = 11) 3. Met with investigator once per week for 30 minutes of group stretching exercises (n = 12) |
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Outcomes | Beck Depression Inventory‐II | |
Notes | Analysis not intention‐to‐treat BDI‐II self‐rated depression score |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Unclear; not described |
Blinding (performance bias and detection bias) participants | Unclear risk | Participants not blind to treatment allocation |
Blinding (performance bias and detection bias) those delivering intervention | Unclear risk | Those delivering the intervention were not blind |
Blinding (performance bias and detection bias) outcome assessors | High risk | BDI‐II self report was used as the primary outcome |
Incomplete outcome data (attrition bias) All outcomes | High risk | 16/54 dropped out (3/18 in high dose, 7/18 in low dose and 6/18 in control) |
Selective reporting (reporting bias) | Unclear risk | It appears that all prespecified outcomes are reported, but no protocol |
Other bias | Unclear risk | Unclear |