Hoffman 2010.

Methods	RCT
Participants	People with a history of traumatic brain injury occurring between 6 months and 5 years prior to trial with at least mild depression (n = 80)
Interventions	1. Aerobic exercise of participant's choosing. 60 minutes of gym‐based supervised exercise per week and 4 x 30‐minute home exercise sessions per week (n = 40; 38% men) 2. No intervention in control group (n = 40; 50% men)
Outcomes	Beck Depression Inventory Score
Notes	The control group were informed they could participate in exercise programme post‐trial intervention period. Authors report that both intervention and control groups showed a substantial increase in exercise. SDs received from author
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Participation open to anyone who met inclusion criteria. Random distribution of sealed envelopes.
Allocation concealment (selection bias)	Low risk	Use of sealed envelopes
Blinding (performance bias and detection bias) participants	Unclear risk	All participants informed of nature of the study and both groups increased total amount of exercise over study period
Blinding (performance bias and detection bias) those delivering intervention	Unclear risk	No detail provided
Blinding (performance bias and detection bias) outcome assessors	High risk	BDI self report
Incomplete outcome data (attrition bias) All outcomes	Low risk	No evidence of missing data
Selective reporting (reporting bias)	Low risk	All findings reported
Other bias	Unclear risk	Unclear