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. 2013 Sep 12;2013(9):CD004366. doi: 10.1002/14651858.CD004366.pub6

McCann 1984.

Methods RCT (parallel group)
Participants Undergraduate psychology students with a requirement to participate in a research project
 No details of age
 100% women
 N = 47
Interventions 1. Aerobic exercise: group running, jogging or dancing for 1 hour twice weekly for 10 weeks (n = 16 randomised)
 2. Placebo control group ‐ muscle relaxation for 15 ‐ 20 minutes 4 times a week (n = 15 randomised)
 3. Waiting list control (n = 16 randomised)
Outcomes Beck Depression Inventory
Notes Outcome assessment not blind
 Analysis not intention‐to‐treat
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information
Allocation concealment (selection bias) High risk Classified as inadequate by Lawlor and Hopker
Blinding (performance bias and detection bias) 
 participants Unclear risk Participants not blind
Blinding (performance bias and detection bias) 
 those delivering intervention Unclear risk Those delivering intervention not blind
Blinding (performance bias and detection bias) 
 outcome assessors High risk Self report depression scores
Incomplete outcome data (attrition bias) 
 All outcomes High risk 4/47 withdrew (1 from the aerobic exercise, 1 from the placebo condition and 2 from the 'no treatment' condition). 43 remained
Selective reporting (reporting bias) Unclear risk No prespecified outcomes. Reported depression scores before and after the intervention. No protocol
Other bias Unclear risk Unclear