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. 2013 Sep 12;2013(9):CD004366. doi: 10.1002/14651858.CD004366.pub6

Singh 2005.

Methods RCT
Participants People responding to a postal questionnaire who had DSM‐IV depression or dysthymia
 Mean age 69
 55% women
 N = 60
Interventions 1. Progressive resistance training at 80% of 1 repetition max (n = 20)
 2. Resistance training at 20% of 1 repetition max (n = 20)
 3. Usual care (n = 20)
Each intervention group held 3 times a week for 8 weeks
Outcomes 1. Hamilton Rating Scale for depression
 2. Geriatric Depression score
Notes Not intention‐to‐treat (50/60 completed the study and were available for assessment)
 Outcome assessment blind
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated random numbers
Allocation concealment (selection bias) Low risk Adequate. Sealed opaque envelopes open after baseline assessment
Blinding (performance bias and detection bias) 
 participants Unclear risk Participants not blind, unclear effect on bias
Blinding (performance bias and detection bias) 
 those delivering intervention Unclear risk Those delivering the intervention were not blind to treatment allocation, unclear effect on bias
Blinding (performance bias and detection bias) 
 outcome assessors Low risk HRSD performed by blinded outcome assessors
Incomplete outcome data (attrition bias) 
 All outcomes High risk 6/60 dropped out (2 from the high‐dose, 3 from the low‐dose and 1 from the usual care group)
Selective reporting (reporting bias) Unclear risk Prespecified outcomes in paper were reported, but no protocol
Other bias Unclear risk Unclear