Table 1.
Laboratory parameters and disease severity between both groups at baseline
| Parameter | PTX (n = 25) | FMT (n = 47) | P-value |
|---|---|---|---|
| Age (years) | 47.7 ± 9.9 | 45.2 ± 10.2 | 0.321 |
| Ascites Grade 2 and above | 18 (72.0%) | 31 (65.9%) | 0.059 |
| Encephalopathy Grade 2 and above | 15 (60.0%) | 30 (63.8%) | 0.753 |
| Hemoglobin (g/L) | 10.4 ± 2.2 | 10.1 ± 1.6 | 0.509 |
| Total leuacocyte count (× 109/L) | 18.3 ± 8.4 | 15.6 ± 9.3 | 0.229 |
| Platelet counta (× 109/L) | 52 (43–516) | 104 (29–282) | 0.134 |
| Total bilirubin (mg/dL) | 21.9 ± 11.6 | 21.2 ± 11.5 | 0.807 |
| AST (U/L) | 162.6 ± 92.5 | 145.3 ± 63.8 | 0.353 |
| ALT (U/L) | 52.5 ± 29.1 | 51.8 ± 30.1 | 0.924 |
| Albumin (g/dL) | 2.4 ± 0.4 | 2.3 ± 0.4 | 0.316 |
| INR | 2.2 ± 0.7 | 2.3 ± 0.6 | 0.527 |
| Blood urea nitrogena (mg/dL) | 35.5 (14–122) | 34 (10–130) | 0.158 |
| Serum creatinine (mg/dL) | 1.1 ± 0.7 | 1.2 ± 0.5 | 0.485 |
| Serum sodium (mmol/L) | 129.3 ± 5.3 | 130.6 ± 4.6 | 0.282 |
| CTPa | 13 (11–14) | 12 (10–15) | 0.068 |
| MELD | 28.2 ± 6.3 | 28.1 ± 4.7 | 0.939 |
| MDFa | 79.8 (45.1–166.9) | 90.7 (45.6–199.2) | 0.269 |
PTX, pentoxifylline; FMT, fecal microbiota transplantation; AST, aspartate transaminase; ALT, alanine transaminase; INR, international normalized ratio; CTP, Child Turcotte Pugh score; MELD, model for end-stage liver disease; MDF, Maddrey’s discriminant function.
a
Values given in median (range).