A. SCA/VA outcome in the overall population
B. MACE outcome in the overall population
C. SCA/VA outcome in the subgroup with history of HF
D. MACE outcome in the subgroup with history of HF
E. SCA/VA outcome in the subgroup without history of HF
F. MACE outcome in the subgroup without history of HF
Kaplan-Meier plots of cumulative incidence for SCA/VA and MACE comparing 1:1 PS-matched hydroxychloroquine vs. methotrexate initiators overall and by history of HF.
Incidence rates between treatment groups are compared with log-rank tests.
ABBREVIATIONS: SCA/VA, sudden cardiac arrest and ventricular arrythmia; MACE, 3-point major adverse cardiac events (i.e., myocardial infarction, stroke, and cardiovascular mortality); HF, heart failure.