. 2022 Nov 17;30:596–605. doi: 10.1016/j.omtn.2022.11.012

Table 2.

Differentially methylated regions in leukocyte DNA between HPV(+) and HPV(−) OPSCC patients

Chromosome	Gene	Discovery		Internal validation		External validation
Chromosome	Gene	Δβ value^a	p value	Δβ value^a	p value	Δβ value^a	p value
Chr5	Nc886	0.130	0.003	0.100	0.001	0.046	0.042
Chr11	CAT	−0.091	0.006	−0.033	0.020	−0.012	0.020
Chr12	GLIPR1L2	−0.120	0.010	−0.062	0.009	0.008	0.321
Chr6	PTCHD4	−0.054	0.049	−0.034	0.032	−0.002	0.759

Δβ value is the difference of the mean β of all the CpG sites in the DMR between HPV(+) and HPV(−) patients.