Figure 2.

tSNE Plots show that the aggregate biomarkers for persons who did or did not later acquire HIV was highly distinct at study entry, but was indistinguishable at the last HIV negative visit

T stochastic neighbor embedding (tSNE) of all 10 biomarkers collected at each visit which evaluates the total distance between individuals across the first two dimensions shows visual clustering of participants who are more similar to each other across the selected parameters. There is clear clustering of cases who would later acquire HIV at enrollment, but they are completely intermixed with controls at the last HIV negative visit.