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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Am J Psychiatry. 2022 Sep 21;179(12):959–968. doi: 10.1176/appi.ajp.20220216

Table 1.

Clinical and demographic characteristics of the randomized (intent-to-treat) sample

Full intent-to-treat sample (n=154) Ketamine+active ASAT sample (n=53) Ketamine+sham ASAT sample (n=50) Saline+active ASAT sample (n=51)

Race/ethnicity
Non-Hispanic Caucasian, n (%) 116 (75.32%) 39 (73.58%) 37 (74.00%) 40 (78.43%)
Hispanic/Latino, n (%) 11 (7.14%) 5 (9.43%) 2 (4.00%) 4 (7.84%)
African American, n (%) 7 (4.55%) 3 (5.66%) 2 (4.00%) 2 (3.92%)
Asian, n (%) 9 (5.84%) 4 (7.55%) 2 (4.00%) 3 (5.88%)
More than one race, n (%) 11 (7.14%) 2 (3.77%) 5 (10.00%) 4 (7.84%)
Unknown/incomplete info, n (%) 3 (1.95%) 0 (0.00%) 2 (4.00%) 1 (1.96%)
Sex
Assigned female sex at birth, n (%) 97 (63.0%) 32 (60.4%) 32 (64.0%) 33 (64.7%)
Gender
 Cisgender male, n (%) 55 (35.71%) 21 (39.62%) 17 (34.00%) 17 (33.33%)
 Cisgender female, n (%) 90 (58.44%) 29 (54.72%) 28 (56.00%) 33 (64.71%)
 Transgender: female-to-male, n (%) 1 (0.65%) 1 (1.89%) 0 (0.00%) 0 (0.00%)
 Transgender: male-to-female, n (%) 1 (0.65%) 0 (0.00%) 0 (0.00%) 1 (1.96%)
 Non-binary or gender fluid, n (%) 2 (1.30%) 1 (1.89%) 1 (2.00%) 0 (0.00%)
 Gender undisclosed/unknown, n (%) 5 (3.25%) 1 (1.89%) 4 (8.00%) 0 (0.00%)
Age, mean (SD) 34.26 (10.5) 34.7 (10.1) 34.6 (11.6) 33.5 (9.9)
# of failed adequate ADM trials, mean (SD) 2.64 (1.93) 2.66 (1.59) 2.60 (1.67) 2.67 (2.46)
Taking psychotropic medication, n (%) 122 (79.2%) 40 (75.5%) 42 (84.0%) 40 (78.4%)
Comorbid anxiety disorder, n (%) 94 (61.0%) 30 (56.6%) 30 (60.0%) 34 (66.7%)
MADRS total score (pre-infusion baseline) 32.78 (5.3) 32.28 (5.7) 33.48 (4.9) 32.61 (5.1)

Note: No variables in the table above differed as a function of treatment group according to unpaired t-tests (for continuous variables) or Chi-squared tests (for categorical variables) (p’s>.49). ASAT=Automated Self-Association Training; ADM=antidepressant medication