Table 1.
Descriptive characteristics of the study population in the Early Autism Risk Longitudinal Investigation (EARLI) study
| Maternal age full study population | Paternal age full study population | |
|---|---|---|
| (N=163) | (N=80) | |
| Child characteristics, N (%) | ||
| Child sex | ||
| Male | 88 (54.0) | 44 (55.0) |
| Female | 75 (46.0) | 36 (45.0) |
| ASD diagnosis | ||
| ASD | 29/154 (18.8) | 14/76 (18.4) |
| Non-typical | 48/154 (31.2) | 28/76 (36.8) |
| Typical | 77/154 (50.0) | 34/76 (44.7) |
| Quantitative traits | ||
| SRS raw score, mean (SD) | 36.9 (27.9) | 33.9 (25.3) |
| MSEL-ELC score at 12 months, mean (SD) | 201.7 (32.5) | 207.6 (28.6) |
| MSEL-ELC score at 36 months, mean (SD) | 97.8 (21.5) | 98.1 (22.5) |
| VABS composite score at 36 months, mean (SD) | 92.0 (13.2) | 92.6 (11.9) |
| Parent characteristics, N (%) | ||
| Maternal age, mean (SD) | 34.0 (5.0) | 34.2 (4.5) |
| Paternal age, mean (SD) | 35.9 (6.2) | 36.4 (6.2) |
| Maternal race | ||
| White | 105 (66.4) | 54 (72.0) |
| Black | 17 (10.8) | 5 (6.7) |
| Other | 36 (22.8) | 16 (21.3) |
| Maternal ethnicity | ||
| Non-Hispanic | 135 (82.8) | 68 (90.7) |
| Hispanic | 28 (17.2) | 7 (9.3) |
| Maternal education, | ||
| High school or less | 19 (11.7) | 7 (9.5) |
| Some college/college | 97 (59.5) | 39 (52.7) |
| Graduate school or higher | 47 (28.8) | 28 (37.8) |
| Paternal race | ||
| White | 104 (66.2) | 56 (70.9) |
| Black | 19 (12.1) | 4 (5.1) |
| Other | 34 (21.7) | 19 (24.0) |
| Paternal ethnicity | ||
| Non-Hispanic | 130 (80.7) | 67 (84.8) |
| Hispanic | 31 (19.3) | 12 (15.2) |
| Paternal education | ||
| High school or less | 36 (22.4) | 7 (9.0) |
| Some college/college | 88 (54.6) | 44 (56.4) |
| Graduate school or higher | 37 (23.0) | 27 (34.6) |
| Study site, N (%) | ||
| Drexel | 41 (25.2) | 28 (35.0) |
| Johns Hopkins | 39 (23.9) | 20 (25.0) |
| Kaiser Permanente | 52 (31.9) | 20 (25.0) |
| UC Davis | 31 (19.0) | 12 (15.0) |
Note: ASD, autism spectrum disorder; SRS, Social Responsiveness Scale; MSEL, Mullen Scales of Early Learning; MSEL-ELC, Mullen Scales of Early Learning early learning composite; VABS, Vineland Adaptive Behavior Rating Scales. The total sample size for each quantitative trait in the maternal age full study population: N=142 for SRS, N=155 for MSEL-ELC at 12 months, N=153 for MSEL-ELC at 36 months, N=152 for VABS; the total sample size for each quantitative trait in the paternal age full study population: N=66 for SRS, N=77 for MSEL-ECL at 12 months and 36 months, N=76 for VABS.