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. 2022 Dec 6;26(1):105748. doi: 10.1016/j.isci.2022.105748

Figure 3.

Figure 3

Use of a mouse model of mild and severe COVID-19

(A-D) White blood cell count, (B) total protein, (C) soluble receptors for advanced glycation end products (sRAGE), and (D) angiopoietin (ANG)-2 levels in bronchoalveolar lavage fluid (BALF) of mouse models of COVID-19 and controls are shown. Values are presented as means ± SE. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.0001.

(E) Representative lung tissue images of sections stained with hematoxylin and eosin are shown. Scale Bar = 50 μm.

(F) A heatmap constructed from the comprehensive analysis of cytokine levels in the BALF of mouse models of severe COVID-19 versus control mice. †q-value <0.05.