Table 1.
Patient Characteristics by SAT Radiodensity Groups
| SAT Radiodensity | ||||
|---|---|---|---|---|
| Characteristicsa | Low (N = 318) | Middle (N = 2,183) | High (N = 367) | |
| Age (years) | 58.0 (28.0–65.0) | 56.0 (48.0–64.0) | 58.0 (45.0–69.0) | 0.03 |
| Race and Ethnicity | 0.05 | |||
| Non-Hispanic White | 220 (69.2) | 1,351 (61.9) | 245 (66.8) | |
| Black | 18 (5.7) | 164 (7.5) | 32 (8.7) | |
| Hispanic | 38 (11.9) | 259 (11.9) | 32 (8.7) | |
| Asian/Pacific Island | 42 (13.2) | 393 (18.0) | 57 (15.5) | |
| Others | 0 (0) | 16 (0.7) | 1 (0.3) | |
| Stage | 0.09 | |||
| I | 76 (23.9) | 448 (20.5) | 95 (25.9) | |
| II | 135 (42.5) | 1,005 (46.0) | 167 (45.5) | |
| III | 107 (33.6) | 730 (33.4) | 105 (28.6) | |
| ER | 0.06 | |||
| ER+ | 233 (73.3) | 1,653 (75.2) | 296 (80.7) | |
| ER− | 85 (26.7) | 530 (24.3) | 71 (19.3) | |
| PR | 0.21 | |||
| PR+ | 162 (50.9) | 1,207 (55.3) | 211 (57.5) | |
| PR− | 156 (49.1) | 976 (44.7) | 156 (42.5) | |
| HER2 | 0.24 | |||
| HER2+ | 53 (16.7) | 398 (18.2) | 58 (15.8) | |
| HER2− | 246 (77.4) | 1,612 (73.8) | 288 (78.5) | |
| Unknown | 19 (6.0) | 173 (7.9) | 21 (5.7) | |
| Charlson Comorbidity Index | <0.001 | |||
| 0 | 228 (71.7) | 1,621 (74.3) | 252 (68.7) | |
| 1–2 | 74 (23.3) | 471 (21.6) | 78 (21.3) | |
| ≥3 | 16 (5.0) | 91 (4.2) | 37 (10.1) | |
| Smoking | 0.09 | |||
| Current | 26 (8.2) | 211 (9.7) | 51 (13.9) | |
| Former | 93 (29.3) | 608 (27.9) | 103 (28.1) | |
| Never | 199 (62.6) | 1364 (62.5) | 213 (58.0) | |
| BMI (kg/m2) | <0.001 | |||
| <18.5 | 0 (0) | 12 (0.5) | 32 (8.7) | |
| 18.5–24.9 | 61 (19.2) | 693 (31.7) | 222 (60.5) | |
| 25–29.9 | 114 (35.9) | 743 (34.0) | 59 (16.1) | |
| ≥30 | 143 (45.0) | 735 (33.7) | 54 (14.7) | |
| Neutrophil-to-lymphocyte Ratio | 2.3 (1.7–3.0) | 2.1 (1.6–3.0) | 2.4 (1.7–3.5) | <0.001 |
| SAT Areas (cm2) | 291.8 (223.6–386.6) | 232.4 (170.3–314.7) | 109.4 (71.4–191.8) | <0.001 |
| VAT Areas (cm2) | 125.8 (83.1–181.4) | 91.4 (46.2–148.9) | 17.3 (7.3–65.7) | <0.001 |
Abbreviations: BMI, body mass index; CT, computed tomography; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PET/CT, Positron emission tomography/computed tomography; PR, progesterone receptor; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.
a
Continuous variables were presented as median (IQR) and categorical variables as Number (%). Percentages may not add up to 100% because of rounding.
b
P values were calculated using the χ2 test for categorical variables and the Kruskal Wallis test for continuous variable.