Table 3.
AUCs for the differential diagnosis of LVH.
| Echocardiographic view | Validation set | Test set | ||||
|---|---|---|---|---|---|---|
| AUC for HHD | AUC for HCM | AUC for ALCA | AUC for HHD | AUC for HCM | AUC for ALCA | |
| PLAX | 0.954 | 0.974 | 0.976 | 0.949 | 0.968 | 0.951 |
| PSAX | 0.894 | 0.97 | 0.871 | 0.892 | 0.959 | 0.929 |
| A4C | 0.931 | 0.954 | 0.953 | 0.908 | 0.973 | 0.989 |
| A2C | 0.905 | 0.925 | 0.916 | 0.917 | 0.974 | 0.978 |
| A3C | 0.908 | 0.983 | 0.924 | 0.907 | 0.937 | 0.986 |
| Aggregate | 0.958 | 0.988 | 0.993 | 0.962 | 0.982 | 0.996 |
The AUC for each differential diagnosis (HHD, HCM and CA) was calculated in the validation (n = 155) and test sets (n = 155).
A2C apical 2-chamber view, A3C apical 3-chamber view, A4C apical 4-chamber view, PLAX parasternal long-axis view, PSAX parasternal short-axis view, AF atrial fibrillation, BMI body-mass index, ALCA light-chain cardiac amyloidosis, EDD end-diastolic dimension, EDV end-diastolic volume, EF ejection fraction, ESD end-systolic dimension, ESV end-systolic volume, HHD hypertensive heart disease, HCM hypertrophic cardiomyopathy, IVSd interventricular septum at end-diastole, LVPWd left ventricular posterior wall thickness at end-diastole, LVWTmax end-diastolic maximal LV wall thickness, LA left atrium, LAVI left atrial volume index, LV left ventricular, MI mass index, N/A not applicable, PASP pulmonary artery systolic pressure, TR tricuspid regurgitation.